Thursday, 23 February 2017

Little Tikes‬‬-swing sets-swing recall

Little Tikes Recall

This recall involves Little Tikes 2-in-1 Snug’n Secure pink toddler swings. The swings have a pink T-shaped restraint in front with a Little Tikes logo. The swing is suspended by four yellow ropes.  The model number 615573 is molded on the back of the swing seat and there is a manufacturing date code stamp on the back of the seat. The molded INNER arrow of the date code stamp points to “10”, “11”, “12” or “13”, it is included in the recall.  In addition, swings with a date code stamp of “9” on the INNER arrow combined with “43” or higher number stamped on the OUTER are included in this recall. No other date codes or other colored swings are affected.

FALL HAZARD
 
A fall hazard is anything in a workplace that could cause accidental loss of balance or body support and result in falling. 

Members of a workplace are encouraged to foresee falling hazards and eliminate or control them by taking precautionary measures before they cause injuries.


Remedy: 
 
Consumers should immediately stop using the recalled swings and contact Little Tikes for a refund in the form of a credit towards the purchase of another Little Tikes product.
 
 
Ref:
https://www.cpsc.gov/Recalls/2017/little-tikes-recalls-toddler-swings
https://www.safeopedia.com/definition/1751/fall-hazard

Heart S1, S2

HEART S1, S2

Listen normal heart sounds sample from the following pages

https://depts.washington.edu/physdx/heart/tech1.html

Heart sounds are the noises generated by the beating heart and the resultant flow of blood through it. Specifically, the sounds reflect the turbulence created when the heart valves snap shut. In cardiac auscultation, an examiner may use a stethoscope to listen for these unique and distinct sounds that provide important auditory data regarding the condition of the heart.

In healthy adults, there are two normal heart sounds often described as a lub and a dub (or dup), that occur in sequence with each heartbeat. These are the first heart sound (S1) and second heart sound (S2), produced by the closing of the atrioventricular valves and semilunar valves, respectively. In addition to these normal sounds, a variety of other sounds may be present including heart murmurs, adventitious sounds, and gallop rhythms S3 and S4.

Heart murmurs are generated by turbulent flow of blood, which may occur inside or outside the heart. Murmurs may be physiological (benign) or pathological (abnormal). Abnormal murmurs can be caused by stenosis restricting the opening of a heart valve, resulting in turbulence as blood flows through it. Abnormal murmurs may also occur with valvular insufficiency (regurgitation), which allows backflow of blood when the incompetent valve closes with only partial effectiveness. Different murmurs are audible in different parts of the cardiac cycle, depending on the cause of the murmur.
 
Ref :
https://depts.washington.edu/physdx/heart/tech1.html
https://en.wikipedia.org/wiki/Heart_sounds

What is a Chemo Port?

CHEMO PORT

 

A chemotherapy port, sometimes referred to as a mediport, cancer port, or portacath, is a vascular access device that is implanted under the skin so that people with cancer can be given chemotherapy. 

Types of catheters

Catheters are long, narrow, hollow tubes made of soft plastic. Your health care team uses them to give medication into a vein. The medical term for this is intravenous or IV treatment.
IV treatments are often given through a catheter with a small needle. This is called an intravenous catheter, or IV. A nurse puts the needle in your forearm or hand. Besides chemotherapy, you can get fluids or other medications this way. For example, you might get anti-nausea medication in your IV.
Your nurse usually takes out an IV catheter when the day’s treatment ends. It might stay in for 2 or 3 days if it is safely in the vein and not causing discomfort. You get a new IV catheter each time you have treatment.
If it works for your veins, you can get most chemotherapy treatments through an IV catheter. But this might not be the best option. This is because:
  • You might need an IV every week or several days in a row. It can be uncomfortable to be stuck with a needle so often.
  • Your nurse might have difficulty putting a needle in a vein so often.
  • Some chemotherapy damages tissue if not injected directly into the vein.  If the veins in your hands and forearms are small or difficult to put a needle into, the risk is higher that chemotherapy will be injected into tissue around the vein.
Your nurse or doctor may suggest using a bigger catheter. This goes into a large vein in your upper arm or neck.
Your doctor may put this type of catheter completely under the skin. If so, it is connected to a small plastic or metal disc called a port. The entire device is called a port-a-cath. Or, the tip of the catheter can stay outside the body. This lets your nurse put medication into it. When you are not getting treatment, the tip is clamped or capped to keep it closed. Some catheters have 2 or 3 tips. These are called double lumen or triple lumen catheters. This lets your team give more than 1 treatment at once.

Different types of catheters

There are several types of catheters, but they work in similar ways. Which one you have depends on many factors. These include:
  • How long you need cancer treatment
  • Your type of treatment
  • How easy the catheter is to care for
  • Cost
Where your doctor puts your catheter and how it is put in depends on the type. Below is a list of different catheters.
  • Peripherally inserted central catheter (PICC). This is also called a PICC line. A nurse or doctor with special training puts it in a large vein near your elbow. Your team gives you local anesthetic to numb the skin and tissue when it is inserted.
  • Central line, tunneled venous catheter, or Hickman catheter. A nurse or doctor with special training puts this catheter in a large vein under the collarbone. Or it might go into a neck vein. The tube goes under the skin. The tip is usually in the upper chest. Your team gives you local anesthetic or conscious sedation when it is put in. Conscious sedation is medication to help you relax and feel sleepy.
  • Implantable port or port-a-cath. A surgeon or radiologist puts in a port, usually with local anesthesia or conscious sedation. The catheter goes under the skin of your chest or upper arm. 
A port is completely under your skin. You might see or feel a small bump on your chest or arm. But you will not see the tip of the catheter. To give treatment, your nurse may first numb the skin with a cream. Then, your nurse cleans the skin and puts a needle into the port. Treatment or blood samples go through the needle.

Benefits of catheters and ports

A catheter in the upper arm or neck can stay in place for weeks or months. Your team can use it to:
  • Reduce the number of times a nurse or other team member sticks you with a needle. Health care team members call this a needle stick. This helps if you have small or damaged veins. These veins are often harder to take samples from. A catheter can also help if you need blood tests often or are anxious about needles.
  • Give blood transfusions or more than 1 treatment at once.
  • Reduce the risk of tissue and muscle damage. This can happen if medication leaks outside a vein. Leaking is more likely with an IV catheter.
  • Avoid bruising or bleeding if you have bleeding problems, such as low platelet counts.
  • Lets you have some chemotherapy at home instead of the hospital or clinic. Continuous infusion therapy is given this way.
Ports can remain in place for weeks, months, or years. Your team can use a port to:
  • Reduce the number of needle sticks.
  • Give treatments that last longer than 1 day. The needle can stay in the port for several days.
  • Give more than 1 treatment or medication at a time. If this is done, the port has 2 openings.
  • Do blood tests and chemotherapy the same day with 1 needle stick.

Caring for catheters and ports

Each catheter type has potential side effects and risks. These include infections, blockages, and clots. Less common problems are a kink in the catheter under your skin or the catheter or port moving. Talk about side effects and risks with your doctor.
Taking care of your catheter or port reduces the risk of problems. If your catheter has a tip outside your skin, take special care of the tip and area around it. You must also flush the catheter with sterile fluid every day. This keeps it from being blocked. An IV care service can help until you feel comfortable. They can help at home or your doctor’s office.
Your doctor or nurse will give you detailed instructions on taking care of your catheter or port. Typical instructions are:
  • Wash your hands before you touch the catheter. This helps prevent infection.
  • Never touch the catheter tip when the cap is off.
  • Follow instructions on cleaning the area and changing the bandage.
  • Keep air out of the catheter. Make sure the top or clamps are on tight except during treatment.
  • Avoid any breaks or cuts in the catheter.
  • Flush a small amount of fluid into the catheter so it does not get blocked. Your nurse can show you how.
  • Keep the catheter area from going underwater.
A port is completely under your skin, so it needs less care. Ask your team for instructions on caring for the area. Follow the instructions until it heals. You may also need to flush the port so it does not get blocked.

Warning signs of catheter or port problems

Contact your doctor immediately if:
  • The area becomes red, swollen, painful, bruised, or warm.
  • There is a lot of bleeding.
  • You get a fever.
  • Any fluid leaks out.
  • You have shortness of breath or dizziness.
  • The catheter tube outside your body gets longer.
  • You cannot flush the catheter or port with liquid. It seems blocked. Never force fluid into the catheter.

Removing catheters and ports

Your doctor or nurse will take out your catheter or port when you no longer need it.
If you have a PICC line, the doctor or nurse will gently pull the tube until it feels loose. Then they will remove it. This does not usually hurt. You do not normally need anesthesia.
If you have port or neck or chest catheter, your doctor or radiologist will make a small cut in the skin. Then they will gently remove the port or catheter. You may need local anesthesia or conscious sedation.

Ref: http://www.cancer.net/navigating-cancer-care/how-cancer-treated/chemotherapy/catheters-and-ports-cancer-treatment

Sunday, 12 February 2017

PCSK9 inhibitors (PSK9i)

PCSK9 Inhibitors

 

The PCSK9 inhibitors (PSK9i) are a newer class of injectable drugs that have been shown to dramatically lower LDL cholesterol levels, by up to 60% when combined with a statin drug

  1. Repatha generic name: evolocumab 
  2. Praluent generic name: alirocumab

Friday, 10 February 2017

Secondary Prevention of Cardiovascular disease CVD?

Secondary Prevention of Cardiovascular disease CVD?

Secondary prevention of CVD is prevention of a second occurrence of CVD (eg, after a
first occurrence of acute coronary syndrome or a first heart attack), or prevention of a
second occurrence of CVD and blood clotting complications after surgical procedures used
to treat the CVD.

Specific Blood-Thinning Drugs Are Prescribed for Secondary Prevention of CVD 

The choice of blood-thinning drugs for secondary prevention of CVD is individualized to each
patient. Expert recommendations suggest the best choices.
 
The duration of blood-thinning therapy for secondary prevention is also individualized to
each patient. Expert recommendations suggest optimal durations for therapy.
 
The choice of blood-thinning drugs and duration of therapy may change over time as the
patient’s need for therapy changes. 

Ref: www.chestpubs.chestjournal.org 

Primary prevention for myocardial infarction

Primary prevention for myocardial infarction 

Primary prevention means preventing Cardiovascular disease before it occurs.

Primary prevention is preventing a disease from occurring. Primary prevention of CVD
includes preventing the blockage of arteries that bring blood to the heart (coronary artery
disease).

 Coronary artery disease is a complex disorder with a number of known causes. Among
these are conditions that can narrow coronary arteries with build-up of cholesterol and
cellular material.
 
Coronary arteries can be additionally narrowed, or completely blocked, by blood clots.
Complete blockage can cause a heart attack (myocardial infarction). Partial blockage can
cause cardiovascular symptoms (acute coronary syndrome, angina pectoris).
 
Prevention of blood clots in coronary arteries can be essential for primary prevention of
CVD
. The use of blood-thinning drugs may be included in a comprehensive strategy for
primary prevention. Preventive strategy may also include the management of blood
cholesterol level, blood glucose level, and body weight, and physical conditioning.

On the basis of results from many studies and clinical trials, aspirin is the blood-thinning
drug most often recommended for primary prevention of CVD. The recommended
preventive dose is usually 75 to 100 mg taken daily.

Primary prevention usually requires that you take this low dose of aspirin for as long as your
physician tells you to take it—often over many years—as long as your risk factors indicate
you are at risk for CVD.

This decision is made by your physician on the basis of your medical history (your risk for
CVD and your risk for bleeding with aspirin), your family medical history (any “heart trouble”
in your family), physical examination, and results of laboratory tests